SGK1, the New Player in the Game of Resistance: Chemo-Radio Molecular Target and Strategy for Inhibition

SGK1, the New Player in the Game of Resistance: Chemo-Radio Molecular Target and Strategy for Inhibition

The serum- and glucocorticoid-regulated kinase (SGK) family consists of three members, SGK1, SGK2 and SGK3, all displaying serine/threonine kinase activity and sharing structural and functional similarities with the AKT family of kinases. SGK1 was originally described as a key enzyme in the hormonal...

Full description

Bibliographic Details
Main Authors: Cristina Talarico, Vincenzo Dattilo, Lucia D'Antona, Miranda Menniti, Cataldo Bianco, Francesco Ortuso, Stefano Alcaro, Silvia Schenone, Nicola Perrotti, Rosario Amato
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
SGK1
Chemo-resistance
Radio-resistance
RAN/RANBP1
MDM2
SGK1 inhibitors
Online Access:http://www.karger.com/Article/FullText/447885

Internet

http://www.karger.com/Article/FullText/447885

Similar Items