Astrocytic ALKBH5 in stress response contributes to depressive-like behaviors in mice

Astrocytic ALKBH5 in stress response contributes to depressive-like behaviors in mice

Abstract Epigenetic mechanisms bridge genetic and environmental factors that contribute to the pathogenesis of major depression disorder (MDD). However, the cellular specificity and sensitivity of environmental stress on brain epitranscriptomics and its impact on depression remain unclear. Here, we...

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Bibliographic Details
Main Authors: Fang Guo, Jun Fan, Jin-Ming Liu, Peng-Li Kong, Jing Ren, Jia-Wen Mo, Cheng-Lin Lu, Qiu-Ling Zhong, Liang-Yu Chen, Hao-Tian Jiang, Canyuan Zhang, You-Lu Wen, Ting-Ting Gu, Shu-Ji Li, Ying-Ying Fang, Bing-Xing Pan, Tian-Ming Gao, Xiong Cao
Format: Article
Language:English
Published: Nature Portfolio 2024-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-48730-2

Internet

https://doi.org/10.1038/s41467-024-48730-2

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