Single-cell RNA-sequencing and microarray analyses to explore the pathological mechanisms of chronic thromboembolic pulmonary hypertension

ObjectiveThe present study aimed to explore the pathological mechanisms of chronic thromboembolic pulmonary hypertension (CTEPH) using a gene chip array and single-cell RNA-sequencing (scRNA-seq).Materials and methodsThe mRNA expression profile GSE130391 was downloaded from the Gene Expression Omnib...

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Bibliographic Details
Main Authors: Ran Miao, Xingbei Dong, Juanni Gong, Yidan Li, Xiaojuan Guo, Jianfeng Wang, Qiang Huang, Ying Wang, Jifeng Li, Suqiao Yang, Tuguang Kuang, Min Liu, Jun Wan, Zhenguo Zhai, Jiuchang Zhong, Yuanhua Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.900353/full