Non-affinity platform for processing knob-into-hole bispecific antibody

Abstract Bispecific antibodies hold significant potential as next-generation biotherapeutics owing to their ability to simultaneously bind to two targets. However, the development of bispecific antibodies as biotherapeutics has been hindered by the high levels of byproducts produced, including both...

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Bibliographic Details
Main Authors: Xiaoyang Wang, Min Li, Mengting Li, Huoyan Hong, Kai Gao, Puya Zhao
Format: Article
Language:English
Published: SpringerOpen 2024-12-01
Series:Bioresources and Bioprocessing
Subjects:
Online Access:https://doi.org/10.1186/s40643-024-00827-8