Tachykinin acts upstream of autocrine Hedgehog signaling during nociceptive sensitization in Drosophila

Tachykinin acts upstream of autocrine Hedgehog signaling during nociceptive sensitization in Drosophila

Pain signaling in vertebrates is modulated by neuropeptides like Substance P (SP). To determine whether such modulation is conserved and potentially uncover novel interactions between nociceptive signaling pathways we examined SP/Tachykinin signaling in a Drosophila model of tissue damage-induced no...

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Bibliographic Details
Main Authors: Seol Hee Im, Kendra Takle, Juyeon Jo, Daniel T Babcock, Zhiguo Ma, Yang Xiang, Michael J Galko
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-11-01
Series:eLife
Subjects:
nociceptive sensitization
Substance P
Hedgehog
electrophysiology
Trp channels
neuropeptide
Online Access:https://elifesciences.org/articles/10735

Internet

https://elifesciences.org/articles/10735

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