Formulating Resveratrol and Melatonin Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) for Ocular Administration Using Design of Experiments

Formulating Resveratrol and Melatonin Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) for Ocular Administration Using Design of Experiments

Recent studies have demonstrated that Sirtuin-1 (SIRT-1)-activating molecules exert a protective role in degenerative ocular diseases. However, these molecules hardly reach the back of the eye due to poor solubility in aqueous environments and low bioavailability after topical application on the eye...

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Detalhes bibliográficos
Principais autores: Elide Zingale, Angela Bonaccorso, Agata Grazia D’Amico, Rosamaria Lombardo, Velia D’Agata, Jarkko Rautio, Rosario Pignatello
Formato: Artigo
Idioma:English
Publicado em: MDPI AG 2024-01-01
coleção:Pharmaceutics
Assuntos:
SNEDDS
ocular delivery
SIRT-1
stability
experimental design
surfactants
Acesso em linha:https://www.mdpi.com/1999-4923/16/1/125

Internet

https://www.mdpi.com/1999-4923/16/1/125

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