Assessing robustness of hazard ratio estimates to outcome misclassification in longitudinal panel studies with application to Alzheimer's disease.

Analyses of imperfectly assessed time to event outcomes give rise to biased hazard ratio estimates. This bias is a common challenge for studies of Alzheimer's Disease (AD) because AD neuropathology can only be identified through brain autopsy and is therefore not available for most study partic...

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Bibliographic Details
Main Authors: Le Wang, Rebecca A Hubbard, Rod L Walker, Edward B Lee, Eric B Larson, Paul K Crane
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5741229?pdf=render