Effects of rIL2/anti-IL2 antibody complex on chikungunya virus-induced chronic arthritis in a mouse model

Abstract Chikungunya virus (CHIKV) is characterized by disabling joint pain that can cause persistent arthritis in approximately one-fourth of patients. Currently, no standard treatments are available for chronic CHIKV arthritis. Our preliminary data suggest that decreases in interleukin-2 (IL2) lev...

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Bibliographic Details
Main Authors: Sarah R. Tritsch, Abigail J. Porzucek, Arnold M. Schwartz, Abigale M. Proctor, Richard L. Amdur, Patricia S. Latham, Gary L. Simon, Christopher N. Mores, Aileen Y. Chang
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-34578-x