Spatiotemporal material functionalization via competitive supramolecular complexation of avidin and biotin analogs

Spatiotemporal material functionalization via competitive supramolecular complexation of avidin and biotin analogs

Controlled patterning of functionality within hydrogels typically involves complex chemistry. Here, the authors report on a simple competitive binding strategy using avidin and biotin analogs in an injectable biomaterial for spatiotemporally controlled presentation of biochemical stimuli to cells.

Bibliographic Details
Main Authors: Tom Kamperman, Michelle Koerselman, Cindy Kelder, Jan Hendriks, João F. Crispim, Xandra de Peuter, Pieter J. Dijkstra, Marcel Karperien, Jeroen Leijten
Format: Article
Language:English
Published: Nature Portfolio 2019-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12390-4

Internet

https://doi.org/10.1038/s41467-019-12390-4

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