5-Hydroxymethylcytosine (5-hmC) Specific Enrichment

5-Hydroxymethylcytosine (5-hmC) is a newly discovered DNA modification in mammalian genomes. This protocol is to be a highly efficient and selective chemical approach to label and capture 5-hmC, taking advantage of a bacteriophage enzyme that adds a glucose moiety to 5-hmC specifically, which could...

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Bibliographic Details
Main Authors: Keith Szulwach, Chun-Xiao Song, Chuan He, Peng Jin
Format: Article
Language:English
Published: Bio-protocol LLC 2012-08-01
Series:Bio-Protocol
Online Access:https://bio-protocol.org/en/bpdetail?id=242&type=0