Sera of Neuromyelitis Optica Patients Increase BID-Mediated Apoptosis in Astrocytes

Sera of Neuromyelitis Optica Patients Increase BID-Mediated Apoptosis in Astrocytes

Neuromyelitis optica (NMO) is a rare disease usually presenting with bilateral or unilateral optic neuritis with simultaneous or sequential transverse myelitis. Autoantibodies directed against aquaporin-4 (AQP4-IgG) are found in most patients. They are believed to cross the blood–brain barrier, targ...

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Bibliographic Details
Main Authors: Omri Zveik, Ariel Rechtman, Nitzan Haham, Irit Adini, Tamar Canello, Iris Lavon, Livnat Brill, Adi Vaknin-Dembinsky
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
NMO
astrocytes
apoptosis
BID
inflammation
neuroimmunology
Online Access:https://www.mdpi.com/1422-0067/23/13/7117

Internet

https://www.mdpi.com/1422-0067/23/13/7117

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