Role of phenylalanine and valine10 residues in the antimicrobial activity and cytotoxicity of piscidin-1.

Piscidin-1 (Pis-1) is a linear antibacterial peptide derived from mast cells of aquacultured hybrid striped bass that comprises 22 amino acids with a phenylalanine-rich amino-terminus. Pis-1 exhibits potent antibacterial activity against pathogens but is not selective for distinguishing between bact...

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Bibliographic Details
Main Authors: Eunjung Lee, Areum Shin, Ki-Woong Jeong, Bongwhan Jin, Hum Nath Jnawali, Soyoung Shin, Song Yub Shin, Yangmee Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4256409?pdf=render