Time-dependent vaccine efficacy estimation quantified by a mathematical model.

In this paper we calculate the variation of the estimated vaccine efficacy (VE) due to the time-dependent force of infection resulting from the difference between the moment the Clinical Trial (CT) begins and the peak in the outbreak intensity. Using a simple mathematical model we tested the hypothe...

Full description

Bibliographic Details
Main Authors: Jennifer Loria, Vinicius V L Albani, Francisco A B Coutinho, Dimas T Covas, Claudio J Struchiner, Jorge P Zubelli, Eduardo Massad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0285466