Duck gasdermin E is a substrate of caspase-3/-7 and an executioner of pyroptosis

Duck gasdermin E is a substrate of caspase-3/-7 and an executioner of pyroptosis

Gasdermin (GSDM)-mediated cell death is an ancient immune defensive mechanism that plays an essential role in bacteria, fungi, coral, teleost, and mammals. After being cleaved by proteases of hosts or pathogens, amino-terminal (NT) fragment of GSDMs (GSDM-NTs) form pores in the membrane structure of...

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Bibliographic Details
Main Authors: Hanqing Li, Xin Wang, Lanjie Yu, Junwei Wang, Yongsheng Cao, Bo Ma, Wenlong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
duck
gasdermin E
caspaes-3
caspase-7
cleavage
pyroptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1078526/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1078526/full

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