IL4I1 Is Expressed by Head–Neck Cancer-Derived Mesenchymal Stromal Cells and Contributes to Suppress T Cell Proliferation

Amino acids have a primary role in cancer metabolism. Beyond their primary biosynthetic role, they represent also an alternative fuel while their catabolites can influence the epigenetic control of gene expression and suppress anti-tumor immune responses. The accumulation of amino-acid derivatives i...

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Bibliographic Details
Main Authors: Alessio Mazzoni, Manuela Capone, Matteo Ramazzotti, Anna Vanni, Luca Giovanni Locatello, Oreste Gallo, Raffaele De Palma, Lorenzo Cosmi, Francesco Liotta, Francesco Annunziato, Laura Maggi
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/10/10/2111