Development, validation, and estimation of measurement uncertainty for the quantitative determination of nitrosamines in Sartan drugs using liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry

Development, validation, and estimation of measurement uncertainty for the quantitative determination of nitrosamines in Sartan drugs using liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry

In the current study, a feasible and sensitive liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry (LC-APCI-MS/MS) method was developed and validated for the determination of eight nitrosamines in Sartan active pharmaceutical ingredients (APIs). The proposed LC-AP...

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Bibliographic Details
Main Authors: Narendra Kumar Nagendla, Hussain Shaik, Seetha Bala Subrahanyam, Deepika Godugu, Mohana Krishna Reddy Mudiam
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Journal of Chromatography Open
Subjects:
Nitrosamines
LC-MS/MS
Sartans
Measurement uncertainty
Online Access:http://www.sciencedirect.com/science/article/pii/S277239172200024X

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http://www.sciencedirect.com/science/article/pii/S277239172200024X

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