The IL-27 receptor regulates TIGIT on memory CD4+ T cells during sepsis

The IL-27 receptor regulates TIGIT on memory CD4+ T cells during sepsis

Summary: Sepsis is a leading cause of morbidity and mortality associated with significant impairment in memory T cells. These changes include the upregulation of co-inhibitory markers, a decrease in functionality, and an increase in apoptosis. Due to recent studies describing IL-27 regulation of TIG...

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Bibliographic Details
Main Authors: Kristen N. Morrow, Zhe Liang, Ming Xue, Deena B. Chihade, Yini Sun, Ching-wen Chen, Craig M. Coopersmith, Mandy L. Ford
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:iScience
Subjects:
Molecular Biology
Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221000614

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http://www.sciencedirect.com/science/article/pii/S2589004221000614

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