Myocyte-specific overexpressing HDAC4 promotes myocardial ischemia/reperfusion injury

Myocyte-specific overexpressing HDAC4 promotes myocardial ischemia/reperfusion injury

Abstract Background Histone deacetylases (HDACs) play a critical role in modulating myocardial protection and cardiomyocyte survivals. However, Specific HDAC isoforms in mediating myocardial ischemia/reperfusion injury remain currently unknown. We used cardiomyocyte-specific overexpression of active...

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Bibliographic Details
Main Authors: Ling Zhang, Hao Wang, Yu Zhao, Jianguo Wang, Patrycja M. Dubielecka, Shougang Zhuang, Gangjian Qin, Y Eugene Chin, Race L. Kao, Ting C. Zhao
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Molecular Medicine
Subjects:
Histone deacetylase4 (HDAC4)
Ischemia/reperfusion
Myocardial function
Online Access:http://link.springer.com/article/10.1186/s10020-018-0037-2

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http://link.springer.com/article/10.1186/s10020-018-0037-2

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