Proteomics Studies Suggest That Nitric Oxide Donor Furoxans Inhibit In Vitro Vascular Smooth Muscle Cell Proliferation by Nitric Oxide-Independent Mechanisms

Proteomics Studies Suggest That Nitric Oxide Donor Furoxans Inhibit In Vitro Vascular Smooth Muscle Cell Proliferation by Nitric Oxide-Independent Mechanisms

Physiologically, smooth muscle cells (SMC) and nitric oxide (NO) produced by endothelial cells strictly cooperate to maintain vasal homeostasis. In atherosclerosis, where this equilibrium is altered, molecules providing exogenous NO and able to inhibit SMC proliferation may represent valuable antiat...

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Bibliographic Details
Main Authors: Loretta Lazzarato, Laura Bianchi, Annapaola Andolfo, Agnese Granata, Matteo Lombardi, Matteo Sinelli, Barbara Rolando, Marina Carini, Alberto Corsini, Roberta Fruttero, Lorenzo Arnaboldi
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Molecules
Subjects:
atherosclerosis
smooth muscle cell proliferation
nitric oxide
furoxans
small ubiquitin-related modifier 1
proteomics
Online Access:https://www.mdpi.com/1420-3049/28/15/5724

Internet

https://www.mdpi.com/1420-3049/28/15/5724

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