Genomic Characterization of <i>Orf Virus</i> Strain D1701-V (<i>Parapoxvirus</i>) and Development of Novel Sites for Multiple Transgene Expression

Genomic Characterization of <i>Orf Virus</i> Strain D1701-V (<i>Parapoxvirus</i>) and Development of Novel Sites for Multiple Transgene Expression

The <i>Orf virus</i> (ORFV; <i>Parapoxvirus</i>) strain D1701 with an attenuated phenotype and excellent immunogenic capacity is successfully used for the generation of recombinant vaccines against different viral infections. Adaption for growth in Vero cells was accompanied...

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Bibliographic Details
Main Authors: Hanns-Joachim Rziha, Mathias Büttner, Melanie Müller, Ferdinand Salomon, Alena Reguzova, Dominic Laible, Ralf Amann
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Viruses
Subjects:
viral vector
<i>parapoxvirus</i>
<i>Orf virus</i>
ORFV
gene deletion
attenuation
recombinant ORFV
Vero cell adaptation
Online Access:https://www.mdpi.com/1999-4915/11/2/127

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https://www.mdpi.com/1999-4915/11/2/127

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