Evidence of distinct tumour-propagating cell populations with different properties in primary human hepatocellular carcinoma.

Increasing evidence that a number of malignancies are characterised by tumour cell heterogeneity has recently been published, but there is still a lack of data concerning liver cancers. The aim of this study was to investigate and characterise tumour-propagating cell (TPC) compartments within human...

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Main Authors: Federico Colombo, Francesca Baldan, Silvia Mazzucchelli, Ines Martin-Padura, Paola Marighetti, Alessandra Cattaneo, Barbara Foglieni, Marta Spreafico, Silvana Guerneri, Marco Baccarin, Francesco Bertolini, Giorgio Rossi, Vincenzo Mazzaferro, Massimiliano Cadamuro, Marco Maggioni, Luca Agnelli, Paolo Rebulla, Daniele Prati, Laura Porretti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3121782?pdf=render