LOTUS overexpression accelerates neuronal plasticity after focal brain ischemia in mice.

Nogo receptor-1 (NgR1) and its ligands inhibit neuronal plasticity and limit functional recovery after brain damage such as ischemic stroke. We have previously shown that lateral olfactory tract usher substance (LOTUS) antagonizes NgR1-mediated signaling. Here, we investigated whether LOTUS enhances...

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Bibliographic Details
Main Authors: Hajime Takase, Yuji Kurihara, Taka-Akira Yokoyama, Nobutaka Kawahara, Kohtaro Takei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0184258&type=printable