oriD structure controls RepD initiation during rolling-circle replication
Abstract Bacterial antibiotic resistance is often carried by circular DNA plasmids that are copied separately from the genomic DNA and can be passed to other bacteria, spreading the resistance. The chloramphenicol-resistance plasmid pC221 from Staphylococcus aureus is duplicated by a process called...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2018-01-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-18817-6 |