Regulation of Extrasynaptic Glutamatergic Signaling by Polysialylated NCAM in Health and Disease
The neural cell adhesion molecule NCAM is known to mediate cell–to–cell and cell–to–extracellular matrix (ECM) adhesion via homophilic and heterophilic interactions. During brain development, NCAM and the associated glycan, polysialic acid (polySia), play important roles in cell migration proliferat...
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Format: | Article |
Language: | English |
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MDPI AG
2023-04-01
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Series: | Biology and Life Sciences Forum |
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Online Access: | https://www.mdpi.com/2673-9976/21/1/30 |