Regulation of Extrasynaptic Glutamatergic Signaling by Polysialylated NCAM in Health and Disease

The neural cell adhesion molecule NCAM is known to mediate cell–to–cell and cell–to–extracellular matrix (ECM) adhesion via homophilic and heterophilic interactions. During brain development, NCAM and the associated glycan, polysialic acid (polySia), play important roles in cell migration proliferat...

Full description

Bibliographic Details
Main Author: Alexander Dityatev
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biology and Life Sciences Forum
Subjects:
Online Access:https://www.mdpi.com/2673-9976/21/1/30