"Negative vaccination" by specific CD4 T cell tolerisation enhances virus-specific protective antibody responses.
BACKGROUND: Cooperation of CD4+ T helper cells with specific B cells is crucial for protective vaccination against pathogens by inducing long-lived neutralizing antibody responses. During infection with persistence-prone viruses, prolonged virus replication correlates with low neutralizing antibody...
Hoofdauteurs: | , , , , , , , |
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Formaat: | Artikel |
Taal: | English |
Gepubliceerd in: |
Public Library of Science (PLoS)
2007-01-01
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Reeks: | PLoS ONE |
Online toegang: | http://europepmc.org/articles/PMC2048666?pdf=render |