Paracrine stimulation of perinatal lung functional and structural maturation by mesenchymal stem cells

Abstract Background Mesenchymal stem cells (MSCs) were shown to harbor therapeutic potential in models of respiratory diseases, such as bronchopulmonary dysplasia (BPD), the most common sequel of preterm birth. In these studies, cells or animals were challenged with hyperoxia or other injury-inducin...

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Bibliographic Details
Main Authors: Janine Obendorf, Claire Fabian, Ulrich H. Thome, Mandy Laube
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-020-02028-4