Preclinic and clinic effectiveness of gabapentin and pregabalin for treatment of neuropathic pain in rats and diabetic patients

Pregabalin and gabapentin are amino-acid derivatives of gamma-aminobutyric acid. They have a high affinity to the α2δ protein in the central nervous system and both have been shown to be effective for neuropathic pain disorder. The aim of this study was to investigate the efficacy of gabapentin and...

Full description

Bibliographic Details
Main Authors: Slavina Surcheva, Lubina Todorova, Dimitar Maslarov, Mila Vlaskovska
Format: Article
Language:English
Published: Taylor & Francis Group 2017-05-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
Online Access:http://dx.doi.org/10.1080/13102818.2017.1290550