Therian origin of INSL3/RXFP2-driven testicular descent in mammals

Introduction: During early development in most male mammals the testes move from a position near the kidneys through the abdomen to eventually reside in the scrotum. The transabdominal phase of this migration is driven by insulin-like peptide 3 (INSL3) which stimulates growth of the gubernaculum, a...

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Bibliographic Details
Main Authors: Brandon R. Menzies, Gerard A. Tarulli, Stephen R. Frankenberg, Andrew J. Pask
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1353598/full