Distinct signature of altered homeostasis in aging rod photoreceptors: implications for retinal diseases.

Advanced age contributes to clinical manifestations of many retinopathies and represents a major risk factor for age-related macular degeneration, a leading cause of visual impairment and blindness in the elderly. Rod photoreceptors are especially vulnerable to genetic defects and changes in microen...

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Bibliographic Details
Main Authors: Sunil K Parapuram, Radu I Cojocaru, Jessica R Chang, Ritu Khanna, Matthew Brooks, Mohammad Othman, Sepideh Zareparsi, Naheed W Khan, Norimoto Gotoh, Tiziana Cogliati, Anand Swaroop
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2975639?pdf=render