Caspase-1 Dependent IL-1β Secretion and Antigen-Specific T-Cell Activation by the Novel Adjuvant, PCEP

The potent adjuvant activity of the novel adjuvant, poly[di(sodiumcarboxylatoethylphenoxy)phosphazene] (PCEP), with various antigens has been reported previously. However, very little is known about its mechanisms of action. We have recently reported that intramuscular injection of PCEP induces NLR...

Full description

Bibliographic Details
Main Authors: Sunita Awate, Nelson F. Eng, Volker Gerdts, Lorne A. Babiuk, George Mutwiri
Format: Article
Language:English
Published: MDPI AG 2014-06-01
Series:Vaccines
Subjects:
Online Access:http://www.mdpi.com/2076-393X/2/3/500