Impact of protein stability, cellular localization, and abundance on proteomic detection of tumor-derived proteins in plasma.

Impact of protein stability, cellular localization, and abundance on proteomic detection of tumor-derived proteins in plasma.

Tumor-derived, circulating proteins are potentially useful as biomarkers for detection of cancer, for monitoring of disease progression, regression and recurrence, and for assessment of therapeutic response. Here we interrogated how a protein's stability, cellular localization, and abundance af...

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Bibliographic Details
Main Authors: Qiaojun Fang, Kian Kani, Vitor M Faca, Wenxuan Zhang, Qing Zhang, Anjali Jain, Sam Hanash, David B Agus, Martin W McIntosh, Parag Mallick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3146523?pdf=render

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http://europepmc.org/articles/PMC3146523?pdf=render

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