FES null mice demonstrate a reduction in neutrophil dependent pancreatic cancer metastatic burden

Patients with pancreatic ductal adenocarcinoma (PDAC) have a dismal 5-year survival rate of less than 10%, predominantly due to delayed diagnosis and a lack of effective treatment options. In the PDAC tumor microenvironment (TME), neutrophils are among the immune cell types that are most prevalent a...

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Bibliographic Details
Main Authors: Jan E. Strøbech, Pietro Giuriatti, Rikke Stagaard, Paulo De Sepulveda, Sebastian R. Nielsen, Janine T. Erler
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1096499/full