The Antinociceptive Role of Nrf2 in Neuropathic Pain: From Mechanisms to Clinical Perspectives

The Antinociceptive Role of Nrf2 in Neuropathic Pain: From Mechanisms to Clinical Perspectives

Neuropathic pain, a chronic condition resulting from nerve injury or dysfunction, presents significant therapeutic challenges and is closely associated with oxidative stress and inflammation, both of which can lead to mitochondrial dysfunction. The nuclear factor erythroid 2-related factor 2 (Nrf2)...

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Bibliographic Details
Main Authors: Kestutis Petrikonis, Jurga Bernatoniene, Dalia M. Kopustinskiene, Roberto Casale, Sergio Davinelli, Luciano Saso
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Pharmaceutics
Subjects:
neuropathic pain
Nrf2
oxidative stress
inflammation
mitochondria
Online Access:https://www.mdpi.com/1999-4923/16/8/1068

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https://www.mdpi.com/1999-4923/16/8/1068

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