Antitumor activity of the protein kinase inhibitor 1-(β-D-2′-deoxyribofuranosyl)-4,5,6,7-tetrabromo- 1H-benzimidazole in breast cancer cell lines

Abstract Background The protein kinases CK2 and PIM-1 are involved in cell proliferation and survival, the cell cycle, and drug resistance, and they are found overexpressed in virtually all types of human cancer, including breast cancer. In this study, we investigated the antitumor activity of a deo...

Full description

Bibliographic Details
Main Authors: Mirosława Koronkiewicz, Zygmunt Kazimierczuk, Andrzej Orzeszko
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-022-10156-8