Sharp Downregulation of Hub Genes Associated With the Pathogenesis of Breast Cancer From Ductal Carcinoma In Situ to Invasive Ductal Carcinoma

Sharp Downregulation of Hub Genes Associated With the Pathogenesis of Breast Cancer From Ductal Carcinoma In Situ to Invasive Ductal Carcinoma

IntroductionBreast atypical ductal hyperplasia (ADH) and ductal carcinoma in situ (DCIS) are precursor stages of invasive ductal carcinoma (IDC). This study aimed to investigate the pathogenesis of breast cancer by dynamically analyzing expression changes of hub genes from normal mammary epithelium...

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Bibliographic Details
Main Authors: Yao Wang, Faqing Liang, Yuting Zhou, Juanjuan Qiu, Qing Lv, Zhenggui Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
weighted gene correlation network analysis (WGCNA)
breast cancer pathogenesis
laser-capture microdissection (LCM)
tissue microarrays (TMA)
hub gene
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.634569/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.634569/full

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