Cardiometabolic Changes in Sirtuin1-Heterozygous Mice on High-Fat Diet and Melatonin Supplementation

Cardiometabolic Changes in Sirtuin1-Heterozygous Mice on High-Fat Diet and Melatonin Supplementation

A hypercaloric fatty diet predisposes an individual to metabolic syndrome and cardiovascular complications. Sirtuin1 (SIRT1) belongs to the class III histone deacetylase family and sustains anabolism, mitochondrial biogenesis, and fat distribution. Epididymal white adipose tissue (eWAT) is involved...

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Bibliographic Details
Main Authors: Gaia Favero, Igor Golic, Francesca Arnaboldi, Annalisa Cappella, Aleksandra Korac, Maria Monsalve, Alessandra Stacchiotti, Rita Rezzani
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
sirtuin1
melatonin
heart
epididymal adipose tissue
interscapular brown adipose tissue
mitochondria
Online Access:https://www.mdpi.com/1422-0067/25/2/860

Internet

https://www.mdpi.com/1422-0067/25/2/860

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