Docking study, synthesis and antimicrobial evaluation of some novel 4-anilinoquinazoline derivatives

Docking study, synthesis and antimicrobial evaluation of some novel 4-anilinoquinazoline derivatives

A series of novel 4-anilinoquinazoline derivatives were designed and synthesized from benzoic acid through ring closure, chlorination or nucleophilic substitution. The structures of compounds were characterized by IR, 1H-NMR and mass spectroscopy. All synthesized derivatives were screened for their...

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Bibliographic Details
Main Authors: Rezvan Rezaee Nasab, Farshid Hassanzadeh, Ghadam Ali Khodarahmi, Mahboubeh Rostami, Mahmoud Mirzaei, Ali Jahanian-Najafabadi, Mahboubeh Mansourian
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
4-anilinoquinazoline; synthesis; antimicrobial activity; antifungal activity; molecular docking
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2017;volume=12;issue=5;spage=425;epage=433;aulast=Nasab

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http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2017;volume=12;issue=5;spage=425;epage=433;aulast=Nasab

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