Association of CYP2C9*2 Allele with Sulphonylurea-Induced Hypoglycaemia in Type 2 Diabetes Mellitus Patients: A Pharmacogenetic Study in Pakistani Pashtun Population

Association of CYP2C9*2 Allele with Sulphonylurea-Induced Hypoglycaemia in Type 2 Diabetes Mellitus Patients: A Pharmacogenetic Study in Pakistani Pashtun Population

Polymorphism in cytochrome P450 (CYP) 2C9 enzyme is known to cause significant inter-individual differences in drug response and occurrence of adverse drug reactions. Different alleles of the <i>CYP2C9</i> gene have been identified, but the notable alleles responsible for reduced enzyme...

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Bibliographic Details
Main Authors: Asif Jan, Muhammad Saeed, Ramzi A. Mothana, Tahir Muhammad, Naveed Rahman, Abdullah R. Alanzi, Rani Akbar
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Biomedicines
Subjects:
cytochrome P450 (CYP450)
pharmacogenetics
CYP2C9*2 allele
sulphonylurea
hypoglycaemia
Pashtun
Online Access:https://www.mdpi.com/2227-9059/11/8/2282

Internet

https://www.mdpi.com/2227-9059/11/8/2282

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