Multicomponent Solids of Niflumic and Mefenamic Acids Based on Acid-Pyridine Synthon

Multicomponent Solids of Niflumic and Mefenamic Acids Based on Acid-Pyridine Synthon

The present study discusses comparative structural features of fourteen multicomponent solids of two non-steroidal anti-inflammatory drugs, Niflumic and Mefenamic acids, with amine and pyridine-based coformers. All the solids were structurally characterized through PXRD, SCXRD, DSC, and the monophas...

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Bibliographic Details
Main Authors: Vineet Kumar, Pramod Kumar Goswami, Balendra, Shailabh Tewari, Arunachalam Ramanan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Chemistry
Subjects:
cocrystallization
acid-pyridine synthon
intermolecular interactions
ΔpKa rule
hirshfeld surface analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2022.729608/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2022.729608/full

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