Controlling Trophoblast Cell Fusion in the Human Placenta—Transcriptional Regulation of Suppressyn, an Endogenous Inhibitor of Syncytin-1

Controlling Trophoblast Cell Fusion in the Human Placenta—Transcriptional Regulation of Suppressyn, an Endogenous Inhibitor of Syncytin-1

Cell fusion in the placenta is tightly regulated. Suppressyn is a human placental endogenous retroviral protein that inhibits the profusogenic activities of another well-described endogenous retroviral protein, syncytin-1. In this study, we aimed to elucidate the mechanisms underlying suppressyn’s p...

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Bibliographic Details
Main Authors: Jun Sugimoto, Danny J. Schust, Makiko Sugimoto, Yoshihiro Jinno, Yoshiki Kudo
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Biomolecules
Subjects:
suppressyn
syncytin
HERV
placenta
cell fusion
promoter
Online Access:https://www.mdpi.com/2218-273X/13/11/1627

Internet

https://www.mdpi.com/2218-273X/13/11/1627

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