Subchondral Bone Microarchitectural and Mineral Properties and Expression of Key Degradative Proteinases by Chondrocytes in Human Hip Osteoarthritis

Subchondral Bone Microarchitectural and Mineral Properties and Expression of Key Degradative Proteinases by Chondrocytes in Human Hip Osteoarthritis

Background: The purpose of this study was to investigate the relationship between the expression of key degradative enzymes by chondrocytes and the microarchitectural and mineral properties of subchondral bone across different stages of cartilage degradation in human hip osteoarthritis (OA). Methods...

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Bibliographic Details
Main Authors: Yunfei Li, Yulia Liem, Zaitunnatakhin Zamli, Niall Sullivan, Enrico Dall’Ara, Haroon Ahmed, Grace Matilda Sellers, Ashley Blom, Mohammed Sharif
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Biomedicines
Subjects:
cartilage degradation
MMP13
ADAMTS4
subchondral bone remodelling
subchondral bone microarchitecture
tissue mineral density
Online Access:https://www.mdpi.com/2227-9059/9/11/1593

Internet

https://www.mdpi.com/2227-9059/9/11/1593

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