ABO gene editing for the conversion of blood type A to universal type O in Rhnull donor‐derived human‐induced pluripotent stem cells

Abstract The limited availability of red cells with extremely rare blood group phenotypes is one of the global challenges in transfusion medicine that has prompted the search for alternative self‐renewable pluripotent cell sources for the in vitro generation of red cells with rare blood group types....

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Bibliographic Details
Main Authors: Paolo Petazzi, Laia Miquel‐Serra, Sergio Huertas, Cecilia González, Neus Boto, Eduardo Muñiz‐Diaz, Pablo Menéndez, Ana Sevilla, Núria Nogués
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/ctm2.1063