A gene regulatory network controls the balance between mesendoderm and ectoderm at pluripotency exit

Abstract During embryogenesis, differentiation of pluripotent cells into somatic cell types depends both on signaling cues and intrinsic gene expression programs. While the molecular underpinnings of pluripotency are well mapped, much less is known on how mouse embryonic stem cells (mESCs) different...

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Dettagli Bibliografici
Autori principali: Hanna L Sladitschek, Pierre A Neveu
Natura: Articolo
Lingua:English
Pubblicazione: Springer Nature 2019-12-01
Serie:Molecular Systems Biology
Soggetti:
Accesso online:https://doi.org/10.15252/msb.20199043