A gene regulatory network controls the balance between mesendoderm and ectoderm at pluripotency exit

Abstract During embryogenesis, differentiation of pluripotent cells into somatic cell types depends both on signaling cues and intrinsic gene expression programs. While the molecular underpinnings of pluripotency are well mapped, much less is known on how mouse embryonic stem cells (mESCs) different...

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Bibliographic Details
Main Authors: Hanna L Sladitschek, Pierre A Neveu
Format: Article
Language:English
Published: Springer Nature 2019-12-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.20199043