Sex-dependent transcription of cardiac electrophysiology and links to acetylation modifiers based on the GTEx database

Development of safer drugs based on epigenetic modifiers, e.g., histone deacetylase inhibitors (HDACi), requires better understanding of their effects on cardiac electrophysiology. Using RNAseq data from the genotype-tissue-expression database (GTEx), we created models that link the abundance of ace...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Michael P. Pressler, Anelia Horvath, Emilia Entcheva
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Frontiers Media S.A. 2022-07-01
Σειρά:Frontiers in Cardiovascular Medicine
Θέματα:
Διαθέσιμο Online:https://www.frontiersin.org/articles/10.3389/fcvm.2022.941890/full