Sex-dependent transcription of cardiac electrophysiology and links to acetylation modifiers based on the GTEx database

Development of safer drugs based on epigenetic modifiers, e.g., histone deacetylase inhibitors (HDACi), requires better understanding of their effects on cardiac electrophysiology. Using RNAseq data from the genotype-tissue-expression database (GTEx), we created models that link the abundance of ace...

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书目详细资料
Main Authors: Michael P. Pressler, Anelia Horvath, Emilia Entcheva
格式: 文件
语言:English
出版: Frontiers Media S.A. 2022-07-01
丛编:Frontiers in Cardiovascular Medicine
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在线阅读:https://www.frontiersin.org/articles/10.3389/fcvm.2022.941890/full