Splice-Junction-Based Mapping of Alternative Isoforms in the Human Proteome

Summary: The protein-level translational status and function of many alternative splicing events remain poorly understood. We use an RNA sequencing (RNA-seq)-guided proteomics method to identify protein alternative splicing isoforms in the human proteome by constructing tissue-specific protein datab...

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Bibliographic Details
Main Authors: Edward Lau, Yu Han, Damon R. Williams, Cody T. Thomas, Rajani Shrestha, Joseph C. Wu, Maggie P.Y. Lam
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719314974