Compatibility Study of Peptide and Glycerol Using Chromatographic and Spectroscopic Techniques: Application to a Novel Antimicrobial Peptide Cbf-14 Gel

Compatibility Study of Peptide and Glycerol Using Chromatographic and Spectroscopic Techniques: Application to a Novel Antimicrobial Peptide Cbf-14 Gel

The interactions between active pharmaceutical ingredients (APIs) and excipients may lead to API degradation, thereby affecting the safety and efficacy of drug products. Cbf-14 is a synthetic peptide derived from Cathelicidin-BF, showing potential for bacterial and fungal infections. In order to ass...

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Bibliographic Details
Main Authors: Jixue Yang, Yitong Huo, Xin Jin, Meiyun Liu, Yuting Lu, Lingman Ma, Changlin Zhou, Taijun Hang, Min Song
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Pharmaceutics
Subjects:
Cbf-14
peptide preparation
glycerol
aldehydes
Maillard reaction
compatibility study
Online Access:https://www.mdpi.com/1999-4923/15/12/2784

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https://www.mdpi.com/1999-4923/15/12/2784

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