tRF-His-GTG-1 enhances NETs formation and interferon-α production in lupus by extracellular vesicle

tRF-His-GTG-1 enhances NETs formation and interferon-α production in lupus by extracellular vesicle

Abstract Background Hyperactive neutrophil extracellular traps (NETs) formation plays a crucial role in active severe systemic lupus erythematosus (SLE). However, what triggers the imbalance in dysregulated NETs formation in SLE is elusive. Transfer RNA-derived small RNAs (tsRNAs) are novel non-codi...

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Bibliographic Details
Main Authors: Yi-Ming Chen, Kuo-Tung Tang, Hung-Jen Liu, Shih-Ting Huang, Tsai-Ling Liao
Format: Article
Language:English
Published: BMC 2024-07-01
Series:Cell Communication and Signaling
Subjects:
Systemic lupus erythematosus
Platelet
Extracellular vesicles
tRNA-derived small RNA
Neutrophil extracellular traps
Interferon-α
Online Access:https://doi.org/10.1186/s12964-024-01730-7

Internet

https://doi.org/10.1186/s12964-024-01730-7

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