3,4′,5-Trimethoxy-<i>trans</i>-stilbene Alleviates Endothelial Dysfunction in Diabetic and Obese Mice via Activation of the AMPK/SIRT1/eNOS Pathway

3,4′,5-Trimethoxy-<i>trans</i>-stilbene Alleviates Endothelial Dysfunction in Diabetic and Obese Mice via Activation of the AMPK/SIRT1/eNOS Pathway

3,4′,5-trimethoxy-<i>trans</i>-stilbene (TMS) is a methoxylated derivative of resveratrol. Previous studies showed the vaso-protective effects of resveratrol; nevertheless, research on this derivative is scarce. The current study aimed to explore whether TMS can alleviate endothelial dys...

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Bibliographic Details
Main Authors: Chunxiu Zhou, Yi Tan, Baojun Xu, Yitao Wang, Wai-San Cheang
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Antioxidants
Subjects:
3,4′,5-trimethoxy-<i>trans</i>-stilbene
endothelial dysfunction
diabetes
endoplasmic reticulum stress
oxidative stress
Online Access:https://www.mdpi.com/2076-3921/11/7/1286

Internet

https://www.mdpi.com/2076-3921/11/7/1286

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