IL-4/IL-13 Axis in Allergic Rhinitis: Elevated Serum Cytokines Levels and Inverse Association With Tight Junction Molecules Expression

IL-4/IL-13 Axis in Allergic Rhinitis: Elevated Serum Cytokines Levels and Inverse Association With Tight Junction Molecules Expression

The IL-4/IL-13 axis is involved in the pathogenesis of allergic rhinitis (AR). In this study, we investigated the serum cytokines levels of IL-4, IL-5, IL-6, and IL-13 in AR patients, and the transcript expression levels of their receptors (i.e. IL4R, IL5RA, IL6R, and IL13RA1) in nasal epithelial ce...

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Bibliographic Details
Main Authors: Siti Muhamad Nur Husna, Norasnieda Md Shukri, Sharifah Emilia Tuan Sharif, Hern Tze Tina Tan, Noor Suryani Mohd Ashari, Kah Keng Wong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
allergic rhinitis
IL-4
IL4R
IL-13
IL13RA1
tight junction
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.819772/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.819772/full

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